| ncRNA name | hsa-miR-181b |
| ncRNA Category | miRNA |
| Disease name | retinoblastoma (RB) |
| Species | Homo sapiens |
| Tissues/Cell_line | RB cell line HXO-RB44; human umbilical vein endothelial cells (HUVECs) |
| Methods | transfection, qPCR, RT‑PCR, Western blot |
| Expression pattern | up-regulated |
| Functional description | miR-181b was upregulated by hypoxia in retinoblastoma in an HIF-1α-independent manner. miR-181b increased tumor angiogenesis of retinoblastoma cells. Additionally, miR-181b exerts its angiogenic function, at least in part, by inhibiting PDCD10 and GATA6. |
| PubMed ID | 25872572 |
| Year | 2015 |
| Title | Hypoxia-induced miR-181b enhances angiogenesis of retinoblastoma cells by targeting PDCD10 and GATA6. |
| Drug-related ncRNA | NO |
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